Over ten years ago, the Ted Rogers Centre for Heart Research (TRCHR) set out to put engineers, biologists, and clinicians in the same room and see what happens when they take on heart failure together. Dr. Craig Simmons was chosen to lead that effort. A University of...
A person walks into an emergency department with heart failure. Within hours, a doctor must make a consequential call to send them home or admit them to the hospital. Both options run their own risks – admitting the patient can lead to an unnecessary hospitalization...
For researchers studying heart disease, lab-grown heart cells are an essential tool. Created from human stem cells, they offer a powerful way to model disease, test therapies, and better understand heart function. However, the challenge remains that these cells behave...
For children living with cardiomyopathy, heart failure is not always caused by the heart losing its ability to pump. In many cases, the problem is more subtle, but just as serious: the heart becomes stiff and struggles to relax and fill properly between beats. This...
New findings from the UNEARTH CVD research team have shed light on an important but often overlooked aspect of cardiovascular care: the cognitive health of people living with heart failure. Published in Cureus, this new publication is the first study to examine...
The Ted Rogers Centre for Heart Research is proud to celebrate an extraordinary milestone in the career of Dr. Paul Santerre, who has been elected as a Fellow of the National Academy of Inventors (NAI), the highest honour bestowed upon academic inventors. This...
Dr. Rodrigo Fernandez-Gonzalez, University of Toronto, Ted Rogers Centre for Heart Research
Oxidative stress orchestrates cell polarity during embryonic wound repair
Dr. Masakazu Akiyama, Hokkaido University
A mathematical model of collective cell migration based on cell polarity
Dr. Yasuhiro Inoue, Kyoto University
Computational simulation on multiple cell dynamics in tissue deformation
Dr. Naoto Ueno, National Institute for Basic Biology
Calcium dynamics and tissue mechanics of vertebrate neural tube closure
Dr. Shizue Ohsawa, Kyoto University
3D morphogenesis of adult appendages from the folded epithelial sheets in Drosophila
Dr. Shigeru Kondo, Osaka University
The reversed ORIGAMI mechanism that determines the 3D shape of the exoskeleton
Dr. Toru Kawanishi, University of Tokyo
Coordinated tissue elongation in the zebrafish posterior body
Dr. Yue Tong, University of Tokyo
Rotational cell migration: a new logic behind 3D somite morphogenesis
Dr. Hisashi Haga, Hokkaido University
Collective movement and 3D morphogenesis of epithelial cells responding to viscoelastic substrates
Dr. Kenji Matsuno, Osaka University
Cell chirality drives left-right asymmetric morphogenesis
Dr. Takeo Matsumoto, Nagoya Institute of Technology
Biomechanical approaches toward elucidation of mechanical environment in Xenopus laevis embryos
Dr. Rudolf Winklbauer, University of Toronto
Cell-cell attachment mechanisms and the range of adhesion strengths
Dr. Ulrich Tepass, University of Toronto
Integration of polarity, adhesion, cytoskeletal dynamics and vesicle trafficking during epithelial cell ingression
Dr. Yu Sun, University of Toronto
Tools for measuring physical properties in vivo
Dr. Sid Goyal, University of Toronto
Heart development
Dr. Brian Ciruna, University of Toronto
Understanding the causes of idiopathic scoliosis: a twisted ‘tail’ of cilia and CSF defects
Dr. Ran Kafri, University of Toronto
Size sensing mechanisms in animal cells
Dr. Sevan Hopyan, University of Toronto
Mesenchymal cell rearrangements that shape tissue in the mouse embryo
Dr. Jennifer Schwartz, Syracuse University
TBD
Dr. Matthias Merkel, Syracuse University
TBD
Dr. Guy Tanentzapf, University of British Columbia
TBD
Dr. Jie Liang, University of Illinois at Chicago
TBD