On March 5, 2025, The Hospital for Sick Children (SickKids) received a significant breakthrough in pediatric research with an $11.7 million award from Genome Canada. As part of the Canadian Precision Health Initiative, a total of $81 million in...
Strain Measurement Activity
From this learning activity you will:
- Have access to echocardiography images in patients receiving cancer therapy to measure global longitudinal strain (GLS).
- Be able to analyze the cases and send it back for expert review and feedback (personalized).
- Have the ability to compare your diagnosis of cardiotoxicity based on an external reference standard and clinical information.
- Use the personalized feedback to analyze a second set of cases to assess improvement in accuracy.
This activity has been made available for informational and educational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
STEP 1:
Please read the following documents prior to beginning the learning activity:
- Strain Image Selection and Post-Processing Examples
- Negishi et al., 2015. Practical Guidance in Echocardiographic Assessment of Global Longitudinal Strain. JACC.
- For EchoInsight: a step-by-step guide for analyzing strain will be provided from Epsilon once you have signed up with EchoInsight.
- For GE, Philips and Tomtec: please watch Supplemental Videos 1, 6, 10, 12, 13 at the link below which provide step-by-step instructions as to how to analyze strain this software:
STEP 2:
Once you have completed Step 1, please fill out the form below.
Note:
- Some of the cases were diagnosed with cardiotoxicity while others were not.
- Two relevant time points during cancer therapy were chosen. These time points will be discussed during feedback.
- Please follow the instructions very carefully.
If you have any questions, please email our team at babitha.thampinathan@uhn.ca.
Strain Case Study Download Form
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* EchoInsight software and cases are available online, no download required.
GE cases will require the use of participants’ local strain analysis software.