With a mission to support novel approaches to managing and preventing heart failure, the Ted Rogers Centre for Heart Research uses its Innovation Fund to propel emerging research with great potential. The 2024-25 Innovation Fund Seed Grants are currently open and you...
2017 Publication Archive
** Please note that this is not an exhaustive list.
December 2017
Deficiency of natriuretic peptide receptor 2 promotes bicuspid aortic valves, aortic valve disease, left ventricular dysfunction, and ascending aortic dilatations in mice
Blaser M, Wei K, Adams R, Zhou Y, Caruso L, Mirzaei Z, Lam A, Tam R, Zhang H, Heximer S, Henkelman M, Simmons C. Circ Research. Dec. 8, 2017;1 21; 12
Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5
Arnold C, Demirel E, Feldner A, Genové G, Zhang H, Sticht C, Wieland T, Hecker M, Heximer S, Korff T. FASEB J. 2017 Dec 5. pii: fj.201700384RR
Incidence, diagnosis, and management of QT prolongation induced by cancer therapies: a systematic review
Porta-Sánchez A, Gilbert C, Spears D, Amir E, Chan J, Nanthakumar K, Thavendiranathan P. J Am Heart Assoc. 2017 Dec 7; 6(12).
November 2017
The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice
Baggio LL, Ussher JR, McLean BA, Cao X, Kabir MG, Mulvihill EE, Mighiu AS, Zhang H, Ludwig A, Seeley RJ, Heximer SP, Drucker DJ. Mol Metab. 2017 Nov;6(11):1339-1349
2017 comprehensive update of the Canadian Cardiovascular Society guidelines for the management of heart failure
Ezekowitz JA, O’Meara E, McDonald MA, Abrams H, Chan M, Ducharme A, Giannetti N, Grzeslo A, Hamilton PG, Heckman GA, Howlett JG, Koshman SL, Lepage S, McKelvie RS, Moe GW, Rajda M, Swiggum E, Virani SA, Zieroth S, Al-Hesayen A, Cohen-Solal A, D’Astous M, De S, Estrella-Holder E, Fremes S, Green L, Haddad H, Harkness K, Hernandez AF, Kouz S, LeBlanc MH, Masoudi FA, Ross HJ, Roussin A, Sussex B. Can J Cardiol. 2017 Nov;33(11):1342-1433
A CD103+ conventional dendritic cell surveillance system prevents development of overt heart failure during subclinical viral myocarditis
Clemente-Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, Momen A, Kantores C, Aronoff L, Farno M, Lucas T, Avery J, Zarrin-Khat D, Elsaesser, Razani B, Lavine K, Husain M, Brooks D, Robbins C, Cybulsky M, Epelman S. Immunity. Nov 2017;47:974-989.e8
Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
Jin SC, Homsy J, Zaidi S, Lu Q, Morton S, DePalma SR, Zeng X, Qi H, Chang W, Sierant MC, Hung WC, Haider S, Zhang J, Knight J, Bjornson RD, Castaldi C, Tikhonoa IR, Bilguvar K, Mane SM, Sanders SJ, Mital S, Russell MW, Gaynor JW, Deanfield J, Giardini A, Porter GA Jr, Srivastava D, Lo CW, Shen Y, Watkins WS, Yandell M, Yost HJ, Tristani-Firouzi M, Newburger JW, Roberts AE, Kim R, Zhao H, Kaltman JR, Goldmuntz E, Chung WK, Seidman JG, Gelb BD, Seidman CE, Lifton RP, Brueckner M. Nat Genet. 2017 Nov;49(11):1593-1601
Deriving vascular smooth muscle cells from mesenchymal stromal cells: Evolving differentiation strategies and current understanding of their mechanisms
Zhang X, Bendeck M, Simmons C, Santerre J. Biomaterials. 2017 Nov;145:9-22
Mono vs multilayer fibronectin coatings on polar/hydrophobic/ionic polyurethanes: Altering surface interactions with human monocytes
Gossart A, Battiston KG, Gand A, Pauthe E, Santerre JP. Acta Biomater. 2017 Nov 8. pii: S1742-7061(17)30690-6
A palliative approach for heart failure end-of-life care
Maciver J, Ross HJ. Curr Opin Cardiol. 2017 Nov 10
Predicting survival in heart failure patients with an implantable cardioverter defibrillator: the Heart Failure Meta-Score
Alba AC, Walter SD, Guyatt GH, Levy WC, Fang J, Ross HJ, Lee DS. J Card Fail. 2017 Nov 22. pii: S1071-9164(17)31276-9
Self-management and clinical decision support for patients with complex chronic conditions through the use of smartphone-based telemonitoring: randomized controlled trial protocol
Seto E, Ware P, Logan AG, Cafazzo JA, Chapman KR, Segal P, Ross HJ. JMIR Res Protoc. 2017 Nov 21;6(11):e229
The prognostic significance of frailty compared to peak oxygen consumption and B-type natriuretic peptide in patients with advanced heart failure
Moayedi Y, Duero Posada JG, Foroutan F, Goldraich LA, Alba AC, MacIver J, Ross HJ. Clin Transplant. 2017 Nov 23.
The need for heart failure advocacy in Canada
Virani S, Bains M, Code J, Ducharme A, Harkness K, Howlett J, Ross H, Sussex B, Zieroth S. Can J Card. Nov 2017;33: 1450-1454
Three-dimensional imaging reveals endo(sarco)plasmic reticulum-containing invaginations within the muscle nucleoplasm
Lee SH, Hadipour-Lakmehsari S, Miyake T, Gramolini A. Am J Physiol Cell Physiol. 2017 Nov 22:ajpcell.00141.2017
October 2017
Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
Jin SC, Homsy J, Zaidi S, Lu Q, Morton S, DePalma SR, Zeng X, Qi H, Chang W, Sierant MC, Hung WC, Haider S, Zhang J, Knight J, Bjornson RD, Castaldi C, Tikhonoa IR, Bilguvar K, Mane SM, Sanders SJ, Mital S, Russell MW, Gaynor JW, Deanfield J, Giardini A, Porter GA Jr, Srivastava D, Lo CW, Shen Y, Watkins WS, Yandell M, Yost HJ, Tristani-Firouzi M, Newburger JW, Roberts AE, Kim R, Zhao H, Kaltman JR, Goldmuntz E, Chung WK, Seidman JG, Gelb BD, Seidman CE, Lifton RP, Brueckner M. Nat Genet. 2017 Oct 9
HDL protects against doxorubicin induced cardiotoxicity in a scavenger receptor class B type 1, PI3K, and AKT dependent manner.
Durham K, Chathely K, Mak K, Momen A, Thomas C, Zhao Y, MacDonald M, Curtis J, Husain M, Trigatti B. Am J Physiol Heart Circ Physiol. 2017 Oct 6
Utility of genetics for risk stratification in pediatric hypertrophic cardiomyopathy
Mathew J, Zahavich L, Lafreniere-Roula M, Wilson J, George K, Benson L, Bowdin S, Mital S. Clin Genet. 2017 Oct 20
The relationship between cardiovascular magnetic resonance imaging measurement of extracellular volume fraction and clinical outcomes in adults with repaired tetralogy of Fallot
Hanneman K, Crean A, Wintersperger B, Thavendiranathan P, Nguyen E, Kayedpour C, Wald R. Eur Heart J Cardiovasc Imaging. 2017 Oct 17
Towards engineering distinct multi-lamellated outer and inner annulus fibrosus tissues
Iu J, Santerre JP, Kandel R. J Orthop Res. 2017 Oct 31. doi: 10.1002/jor.23793
September 2017
A local quality initiative to improve follow-up times for patients with heart failure
Schofield T, Duero Posada J, Foroutan F, Alba C, McDonald M, Linghorne M. BMJ Open Qual 2017; 6:e000052
Corrigendum: candidate gene resequencing in a large bicuspid aortic valve-associated thoracic aortic aneurysm cohort: SMAD6 as an important contributor
Gillis E, Kumar AA, Luyckx I, Preuss C, Cannaerts E, van de Beek G, Wieschendorf B, Alaerts M, Bolar N, Vandeweyer G, Meester J, Wünnemann F, Gould RA, Zhurayev R, Zerbino D, Mohamed SA, Mital S, Mertens L, Björck HM, Franco-Cereceda A, McCallion AS, Van Laer L, Verhagen JMA, van de Laar IMBH, Wessels MW, Messas E, Goudot G, Nemcikova M, Krebsova A, Kempers M, Salemink S, Duijnhouwer T, Jeunemaitre X, Albuisson J, Eriksson P, Andelfinger G, Dietz HC, Verstraeten A, Loeys BL; Mibava Leducq Consortium. Front Physiol. 2017 Sep 25;8:730
Effects of slice orientation on reproducibility of sequential assessment of right ventricular volumes and ejection fraction: short-axis vs transverse SSFP cine cardiovascular magnetic resonance
D’Errico L, Lamacie M, Jimenez Juan L, Deva D, Wald R, Ley S, Hanneman K, Thavendiranathan P, Wintersperger B. J Cardiovasc Magn Reson. 2016 Sep 22;18(1):60
Primary mediastinal paraganglioma associated with a familial variant in the succinate dehydrogenase B subunit gene
Samuel N, Ejaz R, Silver J, Ezzat S, Cusimano RJ, Kim R. J Surg Oncol. 2017 Sep 10
August 2017
Combinatorial screening of 3D biomaterial properties that promote myofibrogenesis for mesenchymal stromal cell-based heart valve tissue engineering
Usprech J, Romero DA, Amon CH, Simmons CA. Acta Biomater. 2017 Aug;58:34-43
Zhang X, Bendeck M, Simmons C, Santerre J. Biomaterials. 2017 Aug 15;145:9-22
Hemocompatibility of degrading polymeric biomaterials: degradable polar hydrophobic ionic polyurethane versus poly(lactic-co-glycolic) acid
Brockman KS, Lai BFL, Kizhakkedathu JN, Santerre JP. Biomacromolecules. 2017 Aug 14;18(8):2296-2305
High-risk cardiac surgery as an alternative to transplant or mechanical support in patients with end-stage heart failure
Kawajiri H, Manlhiot C, Ross H, Delgado D, Billia F, McDonald M, Rao V. J Thorac Cardiovasc Surg. 2017 Aug;154(2):517-525
Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice
Cosme J, Guo H, Hadipour-Lakmehsari S, Emili A, Gramolini A. J Proteome Res. 2017 Aug 4;16(8):2836-2847
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test
Lionel AC, Costain G, Monfared N, Walker S, Reuter MS, Hosseini SM, Thiruvahindrapuram B, Merico D, Jobling R, Nalpathamkalam T, Pellecchia G, Sung WWL, Wang Z, Bikangaga P, Boelman C, Carter MT, Cordeiro D, Cytrynbaum C, Dell SD, Dhir P, Dowling JJ, Heon E, Hewson S, Hiraki L, Inbar-Feigenberg M, Klatt R, Kronick J, Laxer RM, Licht C, MacDonald H, Mercimek-Andrews S, Mendoza-Londono R, Piscione T, Schneider R, Schulze A, Silverman E, Siriwardena K, Snead OC, Sondheimer N, Sutherland J, Vincent A, Wasserman JD, Weksberg R, Shuman C, Carew C, Szego MJ, Hayeems RZ, Basran R, Stavropoulos DJ, Ray PN, Bowdin S, Meyn MS, Cohn RD, Scherer SW, Marshall CR. Genet Med. 2017 Aug 3. doi: 10.1038/gim.2017.119
Improving the appropriate use of transthoracic echocardiography: the echo WISELY trial
Bhatia RS, Ivers NM, Yin XC, Myers D, Nesbitt GC, Edwards J, Yared K, Wadhera RK, Wu JC, Kithcart AP, Wong BM, Hansen MS, Weinerman AS, Shadowitz S, Elman D, Farkouh ME, Thavendiranathan P, Udell JA, Johri AM, Chow CM, Hall J, Bouck Z, Cohen A, Thorpe KE, Rakowski H, Picard MH, Weiner RB. J Am Coll Cardiol. 2017 Aug 29;70(9):1135-1144
Novel approaches to the prediction, diagnosis and treatment of cardiac late effects in survivors of childhood cancer: a multi-centre observational study
Skitch A, Mital S, Mertens L, Liu P, Kantor P, Grosse-Wortmann L, Manlhiot C, Greenberg M, Nathan PC. BMC Cancer. 2017 Aug 3;17(1):519
Patterns of CMR measured longitudinal strain and its association with late gadolinium enhancement in patients with cardiac amyloidosis and its mimics
Williams LK, Forero JF, Popovic ZB, Phelan D, Delgado D, Rakowski H, Wintersperger BJ, Thavendiranathan P. J Cardiovasc Magn Reson. 2017 Aug 7;19(1):61
July 2017
Hepatic JAK2 protects against atherosclerosis through circulating IGF-1
Sivasubramaniyam T, Schroer S, Li A, Luk C, Shi S, Besla R, Dodington D, Metherel A, Kitson A, Brunt J, Lopes J, Wagner K, Bazinet R, Bendeck M, Robbins C, Woo M. JCI Insight. 2017 Jul 20;2(14)
Hypoxia-Induced Changes in the Fibroblast Secretome, Exosome, and Whole-Cell Proteome Using Cultured, Cardiac-Derived Cells Isolated from Neonatal Mice.
Cosme J, Guo H, Hadipour-Lakmehsari S, Emili A, Gramolini AO. J Proteome Res. 2017 Jul 6
Left atrial phasic function and its association with atrial fibrillation in patients after transcatheter aortic valve implantation
Poulin F, Thavendiranathan P, Carasso S, Rakowski H, Horlick EM, Osten MD, Cusimano RJ, Woo A. Can J Cardiol. 2017 Jul;33(7):925-932
June 2017
Adrenergic receptor genotypes influence postoperative outcomes in infants in the Single-Ventricle Reconstruction Trial
Ramroop R, Manase G, Lu D, Manase D, Chen S, Kim R, Lee T, Mahle WT, McHugh K, Mitchell M, Tristani-Firouzi M, Wechsler SB, Wilder NS, Zak V, Lafreniere-Roula M, Newburger JW, Gaynor JW, Russell MW, Mital S. J Thorac Cardiovasc Surg. 2017 Jun 24
Adverse cardiac events associated with incident opioid drug use among older adults with COPD
Vozoris NT, Wang X, Austin PC, Lee DS, Stephenson AL, O’Donnell DE, Gill SS, Rochon PA. Eur J Clin Pharmacol. 2017 Jun 29
Barriers to goals of care discussions with patients who have advanced heart failure: results of a multi-centre survey of hospital-based cardiology clinicians
You J, Aleksova N, Ducharme A, MacIver J, Mielniczuk L, Fowler R, Demers C, Clarke B, Parent M, Toma M, Strachan P, Farand P, Isaac D, Zieroth S, Swinton M, Jiang X, Day A, Heyland D, Ross H. J Card Fail. 2017 Jun 22
Candidate gene resequencing in a large bicuspid aortic valve-associated thoracic aortic aneurysm cohort: SMAD6 as an important contributor
Gillis E, Kumar AA, Luyckx I, Preuss C, Cannaerts E, van de Beek G, Wieschendorf B, Alaerts M, Bolar N, Vandeweyer G, Meester J, Wünnemann F, Gould RA, Zhurayev R, Zerbino D, Mohamed SA, Mital S, Mertens L, Björck HM, Franco-Cereceda A, McCallion AS, Van Laer L, Verhagen JMA, van de Laar IMBH, Wessels MW, Messas E, Goudot G, Nemcikova M, Krebsova A, Kempers M, Salemink S, Duijnhouwer T, Jeunemaitre X, Albuisson J, Eriksson P, Andelfinger G, Dietz HC, Verstraeten A, Loeys BL; Mibava Leducq Consortium. Front Physiol. 2017 Jun 13;8:400
Coordinating cell movements in vivo: junctional and cytoskeletal dynamics lead the way
Hunter MV, Fernandez-Gonzalez R. Curr Opin Cell Biol. 2017 Jun 13;48:54-62
Emerging cardiac imaging modalities for the early detection of cardiotoxicity due to anticancer therapies
López-Fernández T, Thavendiranathan P. Rev Esp Cardiol (Engl Ed). 2017 Jun;70(6):487-495
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
Sergin I, Evans TD, Zhang X, Bhattacharya S, Stokes CJ, Song E, Ali S, Dehestani B, Holloway KB, Micevych PS, Javaheri A, Crowley JR, Ballabio A, Schilling JD, Epelman S, Weihl CC, Diwan A, Fan D, Zayed MA, Razani B. Nat Commun. 2017 Jun 7;8:15750
Percutaneous left atrial decompression in adults with refractory cardiogenic shock supported with veno-arterial extracorporeal membrane oxygenation
Alhussein M, Osten M, Horlick E, Ross H, Fan E, Rao V, Billia F. J Card Surg. 2017 Jun;32(6):396-401
Results of a phase I/II multi-center investigation of udenafil in adolescents after fontan palliation
Goldberg DJ, Zak V, Goldstein BH, Chen S, Hamstra MS, Radojewski EA, Maunsell E, Mital S, Menon SC, Schumacher KR, Payne RM, Stylianou M, Kaltman JR, deVries TM, Yeager JL, Paridon SM; Pediatric Heart Network Investigators. Am Heart J. 2017 Jun;188:42-52
Use of clinical exome sequencing in isolated congenital heart disease
Zahavich L, Bowdin S, Mital S. Circ Cardiovasc Genet. 2017 Jun;10(3)
May 2017
Associations between short or long length of stay and 30-Day readmission and mortality in hospitalized patients with heart failure
Sud M, Yu B, Wijeysundera HC, Austin PC, Ko DT, Braga J, Cram P, Spertus JA, Domanski M, Lee DS. JACC Heart Fail. 2017 May 10
Cell and tissue scale forces coregulate Fgfr2-dependent tetrads and rosettes in the mouse embryo
Wen J, Tao H, Lau K, Liu H, Simmons CA, Sun Y, Hopyan S. Biophys J. 2017 May 23;112(10):2209-2218
Closing the care gap: A primer on quality improvement for heart failure clinicians
Moayedi Y, Schofield T, Etchells E, Silver S, Kobulnik J, McQuillan R, Bell C, Linghorne M, Ross H. Circ Heart Fail. 2017 May;10(5). pii: e003722
Effect of experience and training on the concordance and precision of strain measurements
Negishi T, Negishi K, Thavendiranathan P, Cho G, Popescu B, Vinereanu D, Kurosawa K, Penicka M, Marwick T; SUCCOUR Investigators. JACC Cardiovasc Imaging. 2017 May;10(5):518-522.
Generating favorable growth factor and protease release profiles to enable extracellular matrix accumulation within an in vitro tissue engineering environment.
Zhang X, Battiston KG, Labow RS, Simmons CA, Santerre JP. Acta Biomater. 2017 May;54:81-94.
Reevaluating modality of cardiopulmonary exercise testing in patients with heart failure and resynchronization therapy: relevance of heart rate-adaptive pacing
Goldraich L, Ross HJ, Foroutan F, Walker M, Braga J, McDonald MA. J Card Fail. 2017 May;23(5):422-426
Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions.
Durgin BG, Cherepanova OA, Gomez D, Karaoli T, Alencar GF, Butcher JT, Zhou YQ, Bendeck MP, Isakson BE, Owens GK, Connelly JJ. Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H943-H958
April 2017
Advances in heart failure: a review of biomarkers, emerging pharmacological therapies, durable mechanical support and telemonitoring
Moayedi Y, Ross HJ. Clin Sci (Lond). 2017 Apr 1;131(7):553-566
Automated cell tracking identifies mechanically oriented cell divisions during Drosophila axis elongation
Wang MF, Hunter MV, Wang G, McFaul C, Yip CM, Fernandez-Gonzalez R. Development. 2017 Apr 1;144(7):1350-1361
Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure
Kroetsch J, Levy A, Zhang H, Aschar-Sobbi R, Lidington D, Offermanns S, Nedospasov S, Backx P, Heximer S, Bolz S. Nat Commun. 2017 Apr 5;8:14805
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease
Alibhai F, LaMarre J, Reitz C, Tsimakouridze E, Kroetsch J, Bolz S, Shulman A, Steinberg S, Burris T, Oudit G, Martino T. J Mol Cell Cardiol. 2017 Apr;105:24-37
NASA model of “Threat and Error” in pediatric cardiac surgery: patterns of error chains
Hickey E, Pham-Hung E, Nosikova Y, Halvorsen F, Gritti M, Schwartz S, Caldarone CA, Van Arsdell G. Ann Thorac Surg. 2017 Apr;103(4):1300-1307
Shape of my heart: Cell-cell adhesion and cytoskeletal dynamics during Drosophila cardiac morphogenesis
McFaul CM, Fernandez-Gonzalez R. Exp Cell Res. 2017 Apr 5. pii: S0014-4827(17)30184-2
Short length of stay after elective transfemoral transcatheter aortic valve replacement is not associated with increased early or late readmission risk
Sud M, Qui F, Austin PC, Ko DT, Wood D, Czarnecki A, Patel V, Lee DS, Wijeysundera HC. J Am Heart Assoc. 2017 Apr 24
Tension (re)builds: Biophysical mechanisms of embryonic wound repair
Zulueta-Coarasa T, Fernandez-Gonzalez R. Mech Dev. 2017 Apr;144(Pt A):43-52
Urinary adenosine excretion in type 1 diabetes
Rajasekeran H, Lytvyn Y, Bozovic A, Lovshin J, Diamandis E, Cattran D, Husain M, Perkins BA, Advani A, Reich HN, Kulasingam V, Cherney DZ. Am J Physiol Renal Physiol. 2017 Apr 5:ajprenal.00043.2017
March 2017
Cell-cell and cell-ECM adhesions cooperate to organize actomyosin networks and maintain force transmission during Dorsal Closure
Goodwin K, Lostchuck EE, Cramb KM, Zulueta-Coarasa T, Fernandez-Gonzalez R, Tanentzapf G. Mol Biol Cell. 2017 Mar 22. pii: mbc.E17-01-0033.
Clinical genetic testing in pediatric cardiomyopathy: Is bigger better?
Ouellette A, Mathew J, Manickaraj A, Manase G, Zahavich L, Wilson J, George K, Benson L, Bowdin S, Mital S. Clin Genet. 2017 Mar 30
Could MRI be used to image kidney fibrosis? A review of recent advances and remaining barriers
Leung G, Kirpalani A, Szeto S, Deeb M, Foltz W, Simmons C, Yuen D. Clin J Am Soc Nephrol. 2017 Mar 15
Interventions for preventing cardiomyopathy due to anthracyclines: a Bayesian network meta-analysis
Abdel-Qadir H, Ong G, Fazelzad R, Amir E, Lee D, Thavendiranathan P, Tomlinson G. Ann Oncol. 2017 Mar 1;28(3):628-633
Left ventricular dysfunction with trastuzumab therapy: Is primary prevention the best option?
Thavendiranathan P, Amir E. J Clin Oncol. 2017 Mar 10;35(8):820-825
Left ventricular function in children and adolescents with arrhythmogenic right ventricular cardiomyopathy
Chungsomprasong P, Hamilton R, Luining W, Fatah M, Yoo S, Grosse-Wortmann L. Am J Cardiol. 2017 Mar 1;119(5):778-784
Measuring quality of life in advanced heart failure
MacIver J, Wentlandt K, Ross H. Curr Opin Support Palliat Care. 2017 Mar;11(1):12-16
Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression
Simões S, Oh Y, Wang MF, Fernandez-Gonzalez R, Tepass U. J Cell Biol. 2017 Mar 31. pii: jcb.201608038.
Perspective on precision medicine in paediatric heart failure
Fridman M, Mital S. Clin Sci (Lond). 2017 Mar 1;131(6):439-448
Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions
Durgin B, Cherepanova O, Gomez D, Karaoli T, Alencar G, Butcher J, Zhou Y, Bendeck M, Isakson B, Owens G, Connelly J. Am J Physiol Heart Circ Physiol. 2017 Mar 10
February 2017
The association of chronic kidney disease and microalbuminuria with heart failure with preserved vs. reduced ejection fraction.
Nayor M, Larson MG, Wang N, Santhanakrishnan R, Lee DS, Tsao CW, Cheng S, Benjamin EJ, Vasan RS, Levy D, Fox CS, Ho JE. Eur J Heart Fail. 2017 Feb 20
Cardiac overexpression of S100A6 attenuates cardiomyocyte apoptosis and reduces infarct size after myocardial ischemia-reperfusion
Mofid A, Newman NS, Lee PJ, Abbasi C, Matkar PN, Rudenko D, Kuliszewski MA, Chen HH, Afrasiabi K, Tsoporis JN, Gramolini AO, Connelly KA, Parker TG, Leong-Poi H. J Am Heart Assoc. 2017 Feb 7;6(2). pii: e004738
Cardiovascular toxicity of angiogenesis inhibitors in treatment of malignancy
Abdel-Qadir H, Ethier JL, Lee DS, Thavendiranathan P, Amir E. Cancer Treat Rev. 2017 Feb;53:120-127
The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1
Dadson K, Hauck L, Hao Z, Grothe D, Rao V, Mak T, Billia F. Sci Rep. 2017 Feb 2;7:41490
Hands-on surgical training of congenital heart surgery using 3-dimensional print models
Yoo SJ, Spray T, Austin EH 3rd, Yun TJ, van Arsdell GS. J Thorac Cardiovasc Surg. 2017 Feb 9. pii: S0022-5223(17)30184-8
Interleukin-1β is a key biomarker and mediator of inflammatory vascular calcification
Shobeiri N, Bendeck M. Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):179-180
Generating favorable growth factor and protease release profiles to enable extracellular matrix accumulation within an in vitro tissue engineering environment
Zhang X, Battiston KG, Labow RS, Simmons CA, Santerre JP. Acta Biomater. 2017 Feb 24. pii: S1742-7061(17)30143-5.
Geometry and growth of the reconstructed aorta in patients with hypoplastic left heart syndrome and variants
Haller C, Chetan D, Saedi A, Parker R, Van Arsdell GS, Honjo O. J Thorac Cardiovasc Surg. 2017 Feb 14. pii: S0022-5223(17)30222-2
Management of pregnancy in patients with complex congenital heart disease: A scientific statement for healthcare professionals from the American Heart Association
Canobbio MM, Warnes CA, Aboulhosn J, Connolly HM, Khanna A, Koos BJ, Mital S, Rose C, Silversides C, Stout K. Circulation. 2017 Feb 21;135(8):e50-e87
Mechanically assisted bidirectional cavopulmonary shunt in neonates and infants: An acute human pilot study
Honjo O, Merklinger SL, Poe JB, Guerguerian AM, Zhang H, Taylor KL, Van Arsdell GS. J Thorac Cardiovasc Surg. 2017 Feb;153(2):441-447
p53 regulates the cardiac transcriptome
Mak T, Hauck L, Grothe D, Billia F. Proc Natl Acad Sci U S A. 2017 Feb 13. pii: 201621436.
Prognostic impact of SPECT-MPI after renal transplantation.
Abuzeid W, Iwanochko RM, Wang X, Kim SJ, Husain M, Lee DS. J Nucl Cardiol. 2017 Feb;24(1):295-303.
Tension regulates myosin dynamics during Drosophila embryonic wound repair.
Kobb A, Zulueta-Coarasa T, Fernandez-Gonzalez R. J Cell Sci. 2017 Feb 15;130(4):689-696
Transthyretin amyloidosis: an under-recognized neuropathy and cardiomyopathy
Galant N, Westermark P, Higaki J, Chakrabartty A. Clinical Science. Feb 17, 2017, 131(5)395-409
Ventricular thrombosis post-venoarterial extracorporeal membrane oxygenation
Alhussein M, Moayedi Y, Posada J, Ross H, Hickey E, Rao V, Billia F. Circ Heart Fail. 2017 Feb;10(2). pii: e003757