The Rogers Foundation announces a second landmark gift, building on its $130 million gift in 2014, to sustain the Ted Rogers Centre for Heart Research in perpetuity and bring the promise of precision cardiac health to patients across Canada and globally. In 2014, the...
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Seminar: Wolfram Zimmermann, Goettingen, Germany
November 9, 2018 @ 11:00 am - 12:00 pm EST
Translation of Tissue Engineering for Drug Development and Heart Repair
Engineering of human tissue, with a focus on the heart, is a main research topic of the Zimmermann lab. The seminar will touch upon different models of in vitro organogenesis with applications in disease modelling, drug development, and tissue engineered heart repair. Mechanisms underlying self-organization of pluripotent stem cell-derived cardiomyocytes into functional myocardium will be discussed. Examples for the application of Engineered Human Myocardium (EHM) in the preclinical development of therapeutic genome editing in patients with Duchenne Muscular Dystrophy and the translation of tissue engineered heart failure repair into clinical applications will be presented.