Researchers at the Ted Rogers Centre are exploring the genetic causes of heart disease. The resources below have been compiled with our partners to help patients and families understand some of the concepts associated with the genetics of the heart. Patients and families participating in our research studies may come across some of the themes below.
Any prospective or current patients and families may reach out to the Cardiac Genome Clinic team anytime at tedrogers.mailbox@sickkids.ca. The team oversees two interconnected programs:
- Cardiac Genome Clinic (SickKids) – see brochure.
- Cardiac Genome Project (UHN) – see brochure.
Informational videos
I) An introduction to genetics and DNA
What are DNA and genes? [Duration: 01:04]
II) Inheritance and heritable traits
What is inheritance? [02:07]
What are heritable traits? [01:26]
III) Genetic variation
An introduction to genetic variation [01:43]
IV) Genetic testing and results
How does genome sequencing work? [05:39]
Note: Starting at 05:25, the video states CHOP’s commitment to privacy and references three pieces of American legislation: the Health Insurance Portability and Accountability Act (HIPAA), the Genetic Information Nondiscrimination Act (GINA) and the Affordable Care Act. The relevant Canadian legislation for these Acts are the Personal Information Protection and Electronic Documents Act (PIPEDA) and the Genetic Non-Discrimination Act.
V) Pharmacogenetic testing
What is pharmacogenetics testing at SickKids? [04:40]
Thank You
We thank the following institutions for sharing their resources:
- Genetic Science Learning Center, University of Utah
- Roberts Individualized Medical Genetics Center, Children’s Hospital of Philadelphia
- Centre for Genetic Medicine, SickKids