On March 5, 2025, The Hospital for Sick Children (SickKids) received a significant breakthrough in pediatric research with an $11.7 million award from Genome Canada. As part of the Canadian Precision Health Initiative, a total of $81 million in...
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After eight transformative years at the Ted Rogers Centre for Heart Research (TRCHR), Dr. Soror Sharifpoor is embarking on an exciting new chapter in her career. As the Director of Strategy & Translation at the Translational Biology and Engineering Program (TBEP)...
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NorthMiRs Announced as Winner of ECHO PITCH 2024
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Featured Event
ECHO PITCH 2024
Virtual Library
Visit our YouTube channel filled with world-class heart failure educational sessions on diverse topics
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Seminar: Wolfram Zimmermann, Goettingen, Germany
November 9, 2018 @ 11:00 am - 12:00 pm EST
Translation of Tissue Engineering for Drug Development and Heart Repair
Wolfram Zimmermann
Engineering of human tissue, with a focus on the heart, is a main research topic of the Zimmermann lab. The seminar will touch upon different models of in vitro organogenesis with applications in disease modelling, drug development, and tissue engineered heart repair. Mechanisms underlying self-organization of pluripotent stem cell-derived cardiomyocytes into functional myocardium will be discussed. Examples for the application of Engineered Human Myocardium (EHM) in the preclinical development of therapeutic genome editing in patients with Duchenne Muscular Dystrophy and the translation of tissue engineered heart failure repair into clinical applications will be presented.