Cardiomyopathy is a leading cause of heart failure in children, and there are currently no effective treatments. Could emerging therapies that successfully target the root cause of the condition in adults also work well in children? That was the question Dr....
In the realm of cardiac health, an exciting new study has cast light on the intricate details of our hearts, revealing significant differences between the left and right ventricles' fibroblasts. This research, conducted by a team of dedicated scientists from the...
For children diagnosed with complex heart conditions like hypertrophic cardiomyopathy (HCM), the diagnosis can be frightening for families and challenging for healthcare providers since the trajectory of the condition is often uncertain. As a leading cause of sudden...
An innovative cardiovascular start-up, HDAX Therapeutics, is the latest company to win $250,000 in funding following another year of the Ted Rogers Centre for Heart Research’s Entrepreneurship for Cardiovascular Health Opportunities (ECHO) program. The ECHO program...
Several members of the Ted Rogers Centre for Heart Research (TRCHR) participated in Vascular 2023, a five-day conference held in Montreal from October 25-29. The conference is a hallmark event organized by several Canadian specialist and research organizations,...
Researchers at the Ted Rogers Centre for Heart Research have developed an innovative approach to better understanding the complex signaling mechanisms underlying heart failure. A recent publication in the Proceedings of the National Academy of Sciences (PNAS) offers...
Heart failure is caused by a weakened pump or a stiff heart that does not relax properly. If there is a pumping problem, it is called “reduced ejection fraction.” If there is a problem with the heart’s ability to relax, it is called “preserved ejection fraction.”
There are many potential factors at play for how the heart entered such a condition.
In North America, the most common causes of heart failure are ischemic cardiomyopathy (where the heart muscle is weak due to narrowed or blocked arteries around the heart), a previous heart attack, and chronic high blood pressure. For children, it is most commonly congenital heart disease and abnormal heart muscle.
From here, there is an abundance of other factors that could directly cause or influence a state of heart failure. They include:
For a deeper dive into the causes of this disease, please visit our heart failure patient website.
